Acquisition protocol of sequences evaluated in this report
| Sequence | Section Thickness/Voxel Size | TR, Flip Angle | TE | Matrix; Resolution | Pulse Details |
|---|---|---|---|---|---|
| T2WI TSE in 3 orthogonal planes | 5 mm | 3300 ms | 102 ms | ||
| 3D T1WI gradient echo | 1.5 mm | 8.2 ms | 3.62 ms | ||
| 3D FID 31P CSI | 30 × 30 × 25 mm | 2000 ms; 60° | 2.3 ms | 8 × 8 × 8 at 240 × 240 × 200 mm3, FOV extrapolated to 16 × 16 × 16 | |
| 2D 1H-MRSI | 12.5 mm | 1500 ms; 90° | 30 ms | 16 × 16 | |
| 1H single-voxel PRESS | 20 × 20 × 20 mm PRESS localized volume | 3000 ms; 90° | 30 ms | ||
| 1H single-voxel PRESS | 20 × 20 × 20 mm PRESS-localized volume | 3000 ms; 90° | 97 ms | Sinc-shaped excitation pulse (duration 2.6 ms, Slice selection gradient amplitude 33.95 mT/m, BWTP 8.75), Mao refocusing pulse (duration, 2.6 ms, section-refocusing gradient amplitude, 2.7171 mT/m; BWTP 6) |
Note:—MRSI indicates MR spectroscopic imaging; BWTP, bandwidth-time product; FID, free induction decay; CSI, chemical shift imaging.