Table 2:

Key brain neuroimaging findings in zoonotic outbreaks

Zoonotic PathogenBrain Neuroimaging Abnormalities
Hendra virus (HeV)Widespread cortex21
Nipah virus (NiV)Multifocal tiny white matter and others27,31aWidespread cortex27,34,36
SARS-CoVLarge arterial territory infarction (with hemorrhage)45
MERS-CoVMultifocal white matter and others47aLarge arterial territory infarction47aIntracranial hemorrhage48
Ebola virus (EBOV)Multifocal tiny white matter and others52a
Influenza A H1N1 virusBilateral thalamus (with hemorrhage) and others54aMeningeal enhancement55
Streptococcus agalactiae ST283Multifocal subarachnoid space and others65aMeningeal enhancement65
  • a Denotes detected on DWI.