Table 1:

Consensus recommendations for the dosage of GPIIb/IIIa receptor inhibitors18-26

AgentTirofibanEptifibatideAbciximab
Loading dose (IV or IA bolus)12 mcg/kg for30 mina180 mcg/kg for 1–2 min0.25 mg/kg
Maintenance dose (if necessary, IV infusion for 12–24 hours)0.1 mcg/kg/min2 mcg/min0.125 mcg/kg/min
Trade nameAggrastatIntegrilinReoPro
Duration of antiplatelet effect4–8 hours4 hours48 hours

  • Note:—IA indicates intra-arterial.

  • ↵a 0.4 mcg/kg/min.