Mean value [SD] of parameters at the cerebral aqueduct in the study populationa
| All (n = 73) | iNPH Only (n = 41) | iNPH with AD (n = 23) | Control (n = 9) | P1 | P2 | P3 | |
|---|---|---|---|---|---|---|---|
| Dorsal region of the cerebral aqueduct | |||||||
| OSS amplitude | 52.5 [SD, 33.9] | 59.7 [SD, 34.1] | 52.9 [SD, 32.2] | 19.8 [SD, 13.3] | .483 | <.001 | .004 |
| Maximum OSS | 35.9 [SD, 16.0] | 38.7 [SD, 15.5] | 37.3 [SD, 16.1] | 19.7 [SD, 6.3] | .566 | <.001 | .002 |
| Minimum OSS | –16.7 [SD, 19.8] | –21.0 [SD, 20.2] | –15.6 [SD, 18.9] | –0.1 [SD, 9.6] | .277 | .001 | .043 |
| TAWSS | 18.2 [SD, 8.9] | 19.7 [SD, 8.7] | 18.8 [SD, 9.3] | 9.9 [SD, 2.2] | .678 | <.001 | .008 |
| OSI | 0.21 [SD, 0.13] | 0.24 [SD, 0.12] | 0.19 [SD, 0.14] | 0.16 [SD, 0.11] | .234 | .077 | .614 |
| Ventral region of the cerebral aqueduct | |||||||
| OSS amplitude | 27.2 [SD, 28.4] | 36.0 [SD, 32.2] | 18.1 [SD, 19.8] | 11.9 [SD, 11.1] | .022 | .020 | .363 |
| Maximum OSS | 23.6 [SD, 15.9] | 28.8 [SD, 17.9] | 18.2 [SD, 10.9] | 14.2 [SD, 6.4] | .017 | .011 | .246 |
| Minimum OSS | –3.6 [SD, 13.9] | –7.1 [SD, 15.9] | 0.14 [SD, 10.1] | 2.3 [SD, 7.5] | .080 | .091 | .592 |
| TAWSS | 12.2 [SD, 7.1] | 14.3 [SD, 8.1] | 10.1 [SD, 4.9] | 8.1 [SD, 2.7] | .038 | .020 | .458 |
| OSI | 0.13 [SD, 0.15] | 0.15 [SD, 0.15] | 0.10 [SD, 0.14] | 0.11 [SD, 0.15] | .114 | .355 | .910 |
↵a P1 indicates probability value of iNPH only versus iNPH with AD by the Wilcoxon rank sum test; P2, probability value of iNPH only versus controls by the Wilcoxon rank sum test; and P3, probability value of iNPH with AD versus controls by the Wilcoxon rank sum test.