Table 5:

123I-FP-CIT SBRs according to the nigral hyperintensity status on SMWI

PresentLostP Value
All patients
 Striatum3.51 ± 1.152.03 ± 0.61< .001a
 Caudate nucleus4.01 ± 1.202.63 ± 0.92< .001a
 Putamen3.25 ± 1.211.76 ± 0.55< .001a
Patients with PD
 Striatum3.08 ± 0.892.04 ± 0.62< .001a
 Caudate nucleus3.84 ± 1.092.64 ± 0.94< .001a
 Putamen2.73 ± 0.891.77 ± 0.56< .001a
Control participants
 Striatum4.22 ± 1.881.88 ± 0.16< .001a
 Caudate nucleus4.50 ± 1.272.48 ± 0.35< .001a
 Putamen4.12 ± 1.201.60 ± 0.23< .001a
Per-patient basis analysis of the averaged  SBRs among patients with PDBilateral intact nigral hyperintensity (n = 36)Unilateral or bilateral loss of nigral hyperintensity (n = 73)P Value
 Striatum3.16 ± 0.902.13 ± 0.63< .001a
 Caudate nucleus3.89 ± 1.102.76 ± 0.95< .001a
 Putamen2.81 ± 0.881.84 ± 0.55< .001a
  • a P values < .05 indicate statistical significance.