Linear regression analysis in AD—cortical MTRs relate to poorer language function in patients with AD
MTR Region | MMSE, n = 77 | Language Function (CERAD Test: Boston Naming Test), n = 77 | Constructional Praxis (CERAD Test: Figure Copying), n = 73 | ||||||
---|---|---|---|---|---|---|---|---|---|
β | 95% CI | P Valuea | β | 95% CI | P Valuea | β | 95% CI | P Valuea | |
Global cortex | 0.23 | −0.07–1.96 | .06 | 0.31 | 0.19–1.95 | .02 | 0.22 | −0.09–1.24 | .09 |
AD-signature regions | 0.14 | −0.50–1.52 | .32 | 0.28 | −0.02–1.74 | .05 | 0.29 | −0.01–1.32 | .05 |
Global NAWM | 0.17 | −0.24–1.67 | .14 | 0.11 | −0.05–1.23 | .40 | 0.23 | −0.05–1.23 | .07 |
WM hyperintensities | 0.01 | −0.78–0.88 | .91 | -0.01 | −0.81–0.67 | .89 | 0.01 | −0.53–0.59 | .92 |
Note:—β indicates standardized regression coefficient.
↵a Corrected for age, sex, years of education, normalized regional volume, and Fazekas score.