Clinical and imaging information of patients includeda
| All Patients (n = 237) | Minimal Reperfusion (n = 52) | Major Reperfusion (n = 80) | Partial Reperfusion (n = 57) | Unknown Reperfusion (n = 48) | P Value | |
|---|---|---|---|---|---|---|
| Male | 108 (46) | 27 (52) | 39 (49) | 25 (44) | 17 (35) | .3 |
| Age (yr) | 66 [SD, 16] | 64 [SD, 16] | 66 [SD, 16] | 69 [SD, 14] | 64 [SD, 17] | .4 |
| Hypertension | 159 (67) | 39 (75) | 50 (63) | 39 (68) | 31 (65) | .3 |
| Diabetes | 58 (25) | 14 (27) | 18 (23) | 15 (26) | 11 (23) | .8 |
| Dyslipidemia | 97 (41) | 24 (46) | 30 (38) | 30 (53) | 13 (28) | .6 |
| Atrial fibrillation | 73 (31) | 12 (23) | 27 (34) | 21 (37) | 13 (28) | .4 |
| Treatment methods | .004 | |||||
| IV tPA only | 79 (33) | 25 (48) | 18 (22) | 21 (37) | 15 (31) | |
| Direct thrombectomy | 62 (26) | 8 (15) | 29 (36) | 16 (28) | 9 (19) | |
| Bridging therapy | 77 (32) | 13 (25) | 31 (39) | 16 (28) | 17 (35) | |
| No treatment | 19 (8) | 6 (12) | 2 (3) | 4 (7) | 7 (15) | |
| Onset-to-treatment time (hr) | 5.7 (4.7–7.4) | 5.8 (5.2–6.3) | 5.8 (4.6–7.8) | 5.4 (4.6–6.4) | 5.8 (4.9–7.7) | .9 |
| Baseline DWI lesion volume (mL) | 22 (8–57) | 20 (6–63) | 17 (6–43) | 31 (16–83) | 31 (13–61) | .01 |
| Baseline Tmax lesion volume (mL) | 115 (68–173) | 98 (48–158) | 115 (71–160) | 126 (66–188) | 123 (80–171) | .3 |
| PWI/DWI mismatch ratiob | 3.8 (1.9–8.6) | 2.9 (1.4–6.8) | 5.4 (2.3–13.9) | 3.3 (2.0–5.8) | 3.2 (1.6–6.6) | .006 |
| Baseline NIHSS | 14 (10–19) | 13 (8–19) | 15 (9–19) | 16 (10–19) | 14 (11–19) | .3 |
| Symptomatic hemorrhage | 27 (11) | 7 (13) | 8 (10) | 8 (14) | 4 (8) | .1 |
| Reperfusion rate (%) | 69 (15–97) | 0 (0–9) | 100 (92–100) | 55 (37–68) | NA | <.001 |
| Final infarct volume (mL) | 49 (14–108) | 59 (28–204) | 19 (8–62) | 77 (33–149) | 57 (22–112) | <.001 |
| 90-day mRS | 3 (1–4) | 3 (2–4) | 2 (1–3) | 4 (2–5) | 3 (1–4) | <.001 |