Effect of processing on the CNR of optic nerves relative to ipsilateral normal-appearing white matter in cases with optic neuritis and controls with normal optic nerve function
| Sequence Type | Median CNR (25th–75th Percentiles) for Optic Nerves with Optic Neuritis | P Value | Median CNR (25th–75th Percentiles) for Normal Optic Nerves | P Value |
|---|---|---|---|---|
| FL before processing | −1.05 (−46.7−81.3) | <.001 | −12.7 (−86.9−106.9) | .25 |
| FL after processing | 54.4 (−46.7−795.6) | −12.7 (−86.9−137.9) | ||
| CCE before processing | 9.8 (−181.8−129.2) | <.001 | 2.6 (−83.2–179.1) | .50 |
| CCE after processing | 6.2 (−181.8−238.1) | −0.37 (−83.2−66.8) | ||
| ACE before processing | 11.8 (−29.6−267.8) | .03 | −14.3 (−63.1−2.5) | .27 |
| ACE after processing | 93.9 (−29.6−543.3) | −14.3 (−63.1−2.5) |
Note:—FL indicates FLAIR; CCE, coronal CE-T1WI; ACE, axial CE-T1WI.