Diagnostic performance of ADC values in differentiating groups positive for the SDH mutation from those negative for it (both readers’ results)
| ADC Mean (× 10–3 mm2/s) | ADC Maximum (× 10–3 mm2/s) | nADC Mean | nADC Maximum | |
|---|---|---|---|---|
| Cutoff | 1.15/1.17 | 1.80/1.62 | 1.52/1.53 | 2.32/2.07 |
| Sensitivity | 0.90/0.95 | 0.93/0.79 | 0.90/0.95 | 0.93/0.68 |
| Specificity | 0.83/0.78 | 0.94/0.94 | 0.83/0.83 | 0.94/1.00 |
| PPV | 0.90/0.82 | 0.97/0.94 | 0.90/0.86 | 0.97/1.00 |
| NPV | 0.83/0.93 | 0.90/0.81 | 0.83/0.94 | 0.90/0.75 |
| Accuracy | 0.88/0.87 | 0.94 /0.87 | 0.88/0.89 | 0.94/0.84 |
| AUC | 0.87/0.91 | 0.94/0.94 | 0.87/0.91 | 0.94/0.94 |
Note:—PPV indicates positive predictive value; NPV, negative predictive value; AUC, area under the curve.