Prevalence of PTA versus other CHARGE clinical criteria and of the PTA in cases in which the clinical criterion was absent
| Clinical Criterion | Prevalence in Literature12,25 | Prevalence in Our Study (95% CIs) | Prevalence of PTA When the Clinical Criterion Was Absent |
|---|---|---|---|
| PTA | 56%, 14/25 (95% CI, 0.35–0.76) | ||
| Coloboma | 75%–90% | 64%, 16/25 (95% CI, 0.42–0.82) | 55%, 5/9 (95% CI, 0.21–0.86) |
| Choanal atresia | 35%–65% | 40%, 10/25 (95% CI, 0.21–0.61) | 53%, 8/15 (95% CI, 0.27–0.79) |
| CHARGE ear | 95%–100% | 100%, 25/25 (95% CI, 0.86–1) | |
| Cranial nerve dysfunction | 40–>95% | 100%, 25/25 (95% CI, 0.86–1) | |
| Cardiovascular anomalies | 50%–85% | 72%, 18/25 (95% CI, 0.51–0.88) | 57%, 4/7 (95% CI, 0.18–0.9) |
| Gonadal/genitourinary anomalies | 50%–70% | 40%, 10/25 (95% CI, 0.21–0.61) | 67%, 10/15 (95% CI, 0.21–0.61) |
| Clefting, orofacial/larynx | 15%–20% | 32%, 8/25 (95% CI, 0.15–0.53) | 65%, 11/17 (95% CI, 0.38–0.86) |
| Growth deficiency/developmental delay | 70–>90% | 100%, 25/25 (95% CI, 0.86–1) | |
| Tracheoesophageal fistula/anomalies | 15%–20% | 8%, 2/25 (95% CI, 0.01–0.26) | 56%, 13/23 (95% CI, 0.34–0.77) |