Cohort information
| Characteristic | Total, No. (%) |
|---|---|
| Sex | |
| Male | 31 (44) |
| Female | 39 (56) |
| Age at diagnosis (yr) | |
| Median (IQR) | 6.3 (2.3–11.7)a |
| WHO grade | |
| Grade I | 58 (85) |
| Grade II | 10 (15) |
| Molecular subtype | |
| KIAA1549:BRAF fusion | 30 (43) |
| V600E | 19 (27) |
| Wild-type/other | 21 (30) |
| Disease progression | |
| Yes | 30 (43) |
| No | 40 (57) |
| Tumor location | |
| Brainstem | 4 (6) |
| Cerebral hemisphere | 29 (41) |
| OPHG | 14 (20) |
| Posterior fossa | 21 (30) |
| Spinal cord | 2 (3) |
| Brain imaging completed | |
| Yes | 100 |
| No | 0 |
| Spine imaging completed | |
| Yes | 44 (63) |
| No | 26 (37) |
| Metastasis present | |
| Yes, only brain | 0 (0) |
| Yes, only spine | 0 (0) |
| Yes, brain and spine | 4 (6) |
| No | 66 (94) |
Note:—OPHG indicates optic pathway/hypothalamic glioma.
↵a Median/IQR.