MR imaging diagnosis of meningitis with respect to timea
| Time from Presentation to MR Imaging | No. of Patients | Sensitivity | Specificity | PPV | NPV | Accuracy |
|---|---|---|---|---|---|---|
| 1 day | 37 | 82.6% (61.2%–95.1%) | 92.9% (66.1%–99.8%) | 95.0% (74.0%–99.2%) | 76.5% (56.9%–88.9%) | 86.5% (71.2%–95.5%) |
| 3 days | 69 | 80.0% (66.3%–90.0%) | 94.4% (72.7%–99.9%) | 97.6% (85.6%–99.6%) | 63.0% (49.1%–75.0%) | 83.8% (72.9%–91.6%) |
| 7 days | 108 | 83.5% (73.9%–90.7%) | 95.7% (78.1%–99.9%) | 98.6% (91.2%–99.8%) | 61.1% (49.0%–72.2%) | 86.1% (78.1%–92.0%) |
| 10 days | 119 | 80.7% (71.2%–88.1%) | 92.3% (74.9%–99.1%) | 97.4% (90.8%–99.3%) | 57.1% (46.5%–67.2%) | 83.2% (75.2%–89.4%) |
| 14 days | 157 | 75.8% (67.4%–82.9%) | 93.1% (77.23%–99.2%) | 98.0% (92.7%–99.5%) | 46.6% (38.7%–54.6%) | 79.0% (71.8%–85.1%) |
| 21 days | 197 | 70.5% (62.9%–77.3%) | 93.6% (78.6%–99.2%) | 98.3% (93.9%–99.6%) | 37.2% (31.5%–43.2%) | 74.1% (67.4%–80.1%) |
| 30 days | 209 | 67.4% (60.0%–74.2%) | 93.6% (75.6%–99.2%) | 98.4% (94.0%–99.6%) | 33.3% (28.4%–38.6%) | 71.3% (64.7%–77.3%) |
Note:—True positives/True negatives for each time frame as follows: 1 day (19/13), 3 days (41/17), 7 days (71/22), 10 days (75/24), 14 days (97/27), 21 days (117/29), 30 days (178/29).
↵a Numbers in parentheses are 95% confidence intervals.