- Gadolinium-Enhanced T2 FLAIR Is an Imaging Biomarker of Radiation Necrosis and Tumor Progression in Patients with Brain Metastases
Distinguishing radiation necrosis from tumor progression after radiation therapy for brain metastases is challenging on conventional MRI. This study demonstrated higher normalized contrast-enhanced T1 and T2 FLAIR signal intensity for RN. Contrast-enhanced T2 FLAIR signal intensity distinguished RN and TP with an AUC similar to that of DSC perfusion.