Regular ArticleThe Relationship between Carotid Plaque Composition, Plaque Morphology, and Neurologic Symptoms
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A review of computational methods applied for identification and quantification of atherosclerotic plaques in images
2016, Expert Systems with ApplicationsCitation Excerpt :The composition of atherosclerotic plaques has been addressed as an important factor for evaluating the risks of plaque rupture, as well as risks for embolization and neurological events. Histological analysis of the carotid specimens has proved a higher amount of lipid and cholesterol components in symptomatic plaques when compared to asymptomatic ones (Seeger et al., 1995). Unstable plaques associated with majority of strokes contain features such as hemorrhage, large lipid cores, thrombus and plaque inflammation (Salem et al., 2014).
Plaque hemorrhage in carotid artery disease: Pathogenesis, clinical and biomechanical considerations
2014, Journal of BiomechanicsFeatures of unstable carotid plaque during and after the hyperacute period following TIA/stroke
2013, European Journal of Vascular and Endovascular SurgeryCitation Excerpt :So how should these findings be interpreted? Studies16–18 have shown that a high risk plaque characteristically demonstrates a large lipid core, thin or ruptured cap and marked inflammation in response to healing. This tends to reduce with time.
Ulcerated carotid plaques with ultrasonic echolucency are causatively associated with thromboembolic cerebrovascular events
2013, Journal of Stroke and Cerebrovascular DiseasesCarotid intima-media thickness (cIMT) and plaque from risk assessment and clinical use to genetic discoveries
2012, Perspectives in MedicineCitation Excerpt :Atherosclerosis, including plaque formation, represents a dynamic process involving a complex cascade of inflammatory events from lipid deposition to plaque calcification [35]. There is conflicting evidence about the effect of calcified carotid plaque on cardiovascular events [34,36–38]. Echolucent, fatty plaques are considered more harmful, since they are less stable and therefore more prone to rupture [39].