Abstract
A retrospective analysis of CT and MRI studies in 12 patients with a clinical diagnosis of acute disseminated encephalomyelitis (ADEM) was performed. MRI was the definitive modality for the assessment of the lesions of ADEM: all patients had abnormalities consistent with the clinical diagnosis. Ten had abnormalities in the brain, three spinal cord lesions, and three showed evidence of optic neuritis. CT was normal in 6 of the 7 patients in which it was performed.
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Miller DH, Robb SA, Ormerod IEC, et al (1990) Magnetic resonance imaging of inflammatory and demyelinating white-matter diseases of childhood. Dev Med Child Neurol 32:97–107
Kesselring J, Miller DH, Robb SA, et al (1990) Acute disseminated encephalomyelitis-MRI findings and the distinction from multiple sclerosis. Brain 113:291–302
Atlas SW, Grossman RI, Goldberg HI, Hackney DB, Bilaniuk LT, Zimmerman RA (1986) MR diagnosis of acute disseminated encephalomyelitis. J Comput Assist Tomogr 10:798–801
Alcock NS, Hoffman HL (1962) Recurrent encephalomyelitis in childhood. Arch Dis Child 37:40–44
Donovan MK, Lenn NJ (1989) Postinfectious encephalomyelitis with localized basal ganglia involvement. Pediatr Neurol 5:311–313
Saito H, Endo M, Takase S, Itahara K (1980) Acute disseminated encephalomyelitis after influenza vaccination. Arch Neurol 37: 564–566
Johnson MD, Lavin P, Whetsell WO Jr (1990) Fulminant monophasic multiple sclerosis, Marburg's type. J Neurol Neurosurg Psychiatry 53:918–921
Lukes SA, Norman D (1983) Computed tomography in acute disseminated encephalomyelitis. Ann Neurol 13:567–572
Hart MN, Earle KM (1975) Haemorrhagic and perivenous encephalitis: a clinical-pathological review of 38 cases. J Neurol Neurosurg Psychiatry 38:585–591
Carpenter S, Lampert PW (1968) Postinfectious perivenous encephalitis and acute hemorrhagic encephalitis. In: Minkler J (ed) Pathology of the nervous system, vol 3. McGraw-Hill, New York, pp 2260–2269
Pasternak JF, De Vivo DC, Prensky AL (1980) Steroid-responsive encephalomyelitis in childhood. Neurology 30:481–486
Tolly TL, Wells RG, Sty JR (1989) MR features of fleeting CNS lesions associated with Epstein-Barr virus infection. J Comput Assist Tomogr 13:665–668
Gonzalez-Scarano, Grossman RI, Galetta S, Atlas SW, Silberberg DH (1987) Multiple sclerosis disease activity correlates with gadolinium-enhanced magnetic resonance imaging. Ann Neurol 21:300–306
Miller DH, Newton MR, van der Poel JC, et al (1988) Magnetic resonance imaging of the optic nerve in optic neuritis. Neurology 38:175–179
Bentson J, Reza M, Winter J, Wilson G (1978) Steroids and apparent cerebral atrophy on computed tomography scans. J Comput Assist Tomogr 2:16–23
Caldemeyer KS, Harris TM, Smith RR, Edwards MK (1991) Gadolinium enhancement in acute disseminated encephalomyelitis. J Comput Assist Tomogr 15:673–675
Guy J, Fitzsimmons J, Ellis EA, Mancuso A (1990) Gadolinium-DTPA-enhanced magnentic resonance imaging in experimental optic neuritis. Ophthalmology 97:601–607
Grossman RI, Gonzalez-Scarano F, Atlas SW, Galetta S, Silberberg DH (1986) Multiple sclerosis: gadolinium enhancement in MR imaging. Radiology 161:721–725
Koch KJ, Smith RR (1989) Gd-DTPA enhancement in MR imaging of central pontine myelinolysis. AJNR 10:S58
Bastianello S, Pozzilli C, Bernardi S, et al (1990) Serial study of gadolinium-DTPA MRI enhancement in multiple sclerosis. Neurology 40:591–595
Burnham JA, Wright RR, Dreisbach J, Murray RS (1991) The effect of high-dose steroids on MRI gadolinium enhancement in acute demyelinating lesions. Neurology 41:1349–1354
Crocker EF, Zimmerman RA, Phelps ME, Kuhl DE (1976) The effect of steroids on the extravascular distribution of radiographic contrast material and technetium pertechnetate in brain tumors as determined by computed tomography. Radiology 119: 471–474
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Caldemeyer, K.S., Smith, R.R., Harris, T.M. et al. MRI in acute disseminated encephalomyelitis. Neuroradiology 36, 216–220 (1994). https://doi.org/10.1007/BF00588134
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DOI: https://doi.org/10.1007/BF00588134