Skip to main content
Log in

Retinoblastoma: CT and MRI

  • Head and Neck Radiology
  • Published:
Neuroradiology Aims and scope Submit manuscript

Abstract

To evaluate the effectiveness of CT and MRI at 0.5 T in the diagnosis and staging of retinoblastoma, we studied 11 patients in whom retinoblastoma was clinically suspected. Nine of the eleven had surgically proven retinoblastoma; in the other two a diagnosis of Coat's disease was made. MRI was not as specific as CT for diagnosing retinoblastoma, due to its lack of sensitivity in detecting calcification; it did, however, have superior contrast resolution. On MRI, Coats' discase was reliably diagnosed and easily differentiated from retinoblastoma. Moreover, the greater ability of MRI to differentiate subretinal fluid from tumour also confers high accuracy in measuring tumour size. CT is still the study of choice in the diagnosis of retinoblastoma, but when MRI is available, it should be performed for better differentiation from lesions such as Coats' disease.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Mafee MF (1990) Magnetic resonance imaging: ocular pathology. In: Newton TH, Bilaniuk LT. Radiology of the eye and orbit (Modern neuroradiology, volume 4). Raven Press, New York, pp 311–314, 321–322

    Google Scholar 

  2. Donaldson SS, Smith LM (1989) Retinoblastoma: biology, presentation and current management. Oncology 3:45–52

    Google Scholar 

  3. Abramson DH (1982) Retinoblastoma: diagnosis and management. CA 32: 130–140

    Google Scholar 

  4. Mafee MF, Goldberg MF, Cohen SB, Gotsis ED, Safran M, Chekuri L, Raofi B (1989) Magnetic resonance imaging versus computed tomography of leukocoric eyes and use of in vitro proton magnetic resonance spec troscopy of retinoblastoma. Ophthalmology 96: 965–976

    Google Scholar 

  5. Wilms G, Marchal G, Van Fraeyenhoven L, Demaerel P, Van Hecke P, Baert AL, Dralands G (1991) Shortcomings and pitfalls of ocular MRI. Neuroradiology 33: 320–325

    Google Scholar 

  6. Nucci P, Modorati G, Pierro L, Alfarano R, Brancato R (1989) Comparative evaluation of echography and CAT in diagnosing retinoblastoma. Minerva Pediatr 41: 129–131

    Google Scholar 

  7. Gupta KL, Righi AM, Mihara F, Robinson AE, Haik BG (1991) MRI, ultrasound and surgical correlation of orbital tumors. Neuroradiology 33 [Suppl]: 71

    Google Scholar 

  8. Mafee MF, Goldberg MG, Greenwold JM, et al (1987) Retinoblastoma and simulating lesions: role of CT and MR imaging. Radiol Clin North Am 25: 667–682

    Google Scholar 

  9. Wilms G, Dralands G, Van Fraeyenhoven L, Decrop E, Demaerel P, Van Eyck L, Marchal G, Van Hecke P, Baert AL (1989) Magnetic resonance imaging in lesions of the eye globe. J Belge Radiol 72: 165–172

    Google Scholar 

  10. Peyster RG, Augsberger JJ, Shields JA, Hershey BL, Eagle R, Haskin ME (1988) Intraocular tumors: evaluation with MR imaging. Radiology 168: 773–779

    Google Scholar 

  11. Peyster RG, Augsburger JJ, Shields JA, Herskey BL, Eale R Jr, Haskin ME (1988) Intraocular tumors: evaluation with MR imaging. Radiology 168: 773–779

    Google Scholar 

  12. Weber AL, Mafee MF (1992) Evaluation of the globe using computed tomography and magnetic resonance imaging. Israel J Med Sci 23: 145–152

    Google Scholar 

  13. Holland BA, Kucharczyk W, Brant-Zawadski M, Norman D, Haas DK, Harper PS (1985) MR imaging of calcified intracranial lesions. Radiology 157: 353–356

    Google Scholar 

  14. Oot RF, New PFJ, Pile-Spellman J, Rosen BR, Shoukimas GM, Davis KR (1986) Detection of intracranial calcifications by MR. AJNR 7: 801–809

    Google Scholar 

  15. Edwards JH, Hyman RA, Vacirca SJ, et al (1985) 0.6 T magnetic resonance imaging of the orbit. AJR 144: 1015–1020

    Google Scholar 

  16. Sobel DF, Kelly W, Kjos BO, Char D, Brant-Zawadski M, Norman D (1985) MR imaging of orbital and ocular disease. AJNR 6: 259–264

    Google Scholar 

  17. Haik BG, Saint Louis L, Smith ME et al. (1985) Magnetic resonance imaging in the evaluation of leukocoria. Ophthalmology 92: 1143–1152

    Google Scholar 

  18. Sullivan JA, Harms SE (1987) Characterization of orbital lesions by surface coil MR imaging. Radiographics 7: 9–28

    Google Scholar 

  19. Sullivan JA, Harms SE (1986) Surface coil MR imaging of orbital neoplasm. AJNR 7: 29–34

    Google Scholar 

  20. Scott WA, Bilaniuk LT, Zimmerman RA, Hackney DB, Goldberg HI, Grossman RI (1987) Orbit: initial experience with surface coil spin echo MR imaging at 1.5 T. Radiology 164: 501–509

    Google Scholar 

  21. Okabe H, Kiyosowa M, Mizuno K, Yamada S, Yamada K (1986) Nuclear magnetic resonance imaging of subretinal fluid. Am J Ophthalmol 102: 640–646

    Google Scholar 

  22. Smith EV, Gragoudas ES, Kolodny NH, Amico DJ (1990) Magnetic resonance imaging: an emerging technique for the diagnosis of ocular disorders. Int Ophth 14: 119–124

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Beets-Tan, R.G.H., Hendriks, M.J., Ramos, L.M.P. et al. Retinoblastoma: CT and MRI. Neuroradiology 36, 59–62 (1994). https://doi.org/10.1007/BF00599199

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00599199

Key words

Navigation