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Magnetic resonance imaging in patients with multiple sclerosis and spinal cord involvement: 28 cases

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Abstract

In patients with clinically isolated spinal disease, magnetic resonance imaging (MRI) provides a non-invasive method of detecting surgically treatable causes and is also useful in detecting asymptomatic brain lesions where the cord syndrome is due to multiple sclerosis (MS). We report the findings of spinal and brain MRI in 28 patients with spinal cord disorder due to MS. It was possible to detect intrinsic plaques reliably in the majority of patients (60.7%) with clinical findings of spinal cord MS. The results of MRI are compared with the clinical status and with cerebrospinal fluid findings and evoked potentials.

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References

  1. Asbury AK, Herndon RM, McFarland HF, et al (1987) National Multiple Sclerosis Society Working Group on Neuroimaging for the Medical Advisory Board. Neuroradiology 29:119

    Google Scholar 

  2. Babikian V, Ropper AH (1987) Binswanger's disease: a review. Stroke 18:2–12

    Google Scholar 

  3. Chiappa KH (1990) Evoked potentials in clinical medicine, 2nd edn. Raven Press, New York

    Google Scholar 

  4. Cutler JR, Aminoff MJ, Brant-Zawadzki M (1986) Evaluation of patients with multiple sclerosis by evoked potentials and magnetic resonance imaging: a comparative study. Ann Neurol 20:645–648

    Google Scholar 

  5. Edwards MK, Farlow MR, Stevens JC (1986) Cranial MR in spinal cord MS: diagnosing patients with isolated spinal cord symptoms. AJNR 7:1003–1005

    Google Scholar 

  6. Farlow MR, Markand ON, Edwards MK, Stevens JC, Kolar OJ (1986) Multiple sclerosis: magnetic resonance imaging, evoked responses, and spinal fluid electrophoresis. Neurology 36:828–831

    Google Scholar 

  7. Gilbert JJ, Sadler M (1983) Unsuspected multiple sclerosis. Arch Neurol 40:533–536

    Google Scholar 

  8. Grossman RI, Gonzalez-Scarano F, Atlas SW, et al (1986) Multiple sclerosis: gadolinium enhancement in MR imaging. Radiology 161:721–725

    Google Scholar 

  9. Ikuta F, Zimmerman HM (1976) Distribution of plaques in seventy autopsy cases of multiple sclerosis in the United States. Neurology 26[Suppl]:28–36

    Google Scholar 

  10. Jacobs L, Kinkel WR, Polachini I, Kinkel RP (1986) Correlations of nuclear magnetic resonance imaging, computerized tomography, and clinical profiles in multiple sclerosis. Neurology 36:27–34

    Google Scholar 

  11. Kurtzke JF (1983) Rating neurologic impairment in multiple sclerosis: an expanded disability status scale (EDSS) Neurology 33:1444–1452

    Google Scholar 

  12. Kurtzke JF (1988) Multiple sclerosis: what's in a name. Neurology 38:309–316

    Google Scholar 

  13. Matthews WB (1975) Paroxysmal symptoms in multiple sclerosis. J Neurol Neurosurg Psychiatry 38:617–623

    Google Scholar 

  14. Miller DH, McDonald WI, Blumhardt LD, et al (1987) Magnetic resonance imaging in isolated noncompressive spinal cord syndromes. Ann Neurol 22:714–723

    Google Scholar 

  15. Miller GM, Forbes GS, Onofrio BM (1989) Magnetic resonance imaging of the spine. Mayo Clin Proc 64:986–1004

    Google Scholar 

  16. Poser CM, Paty DW, Scheinberg L, et al (1983) New diagnostic criteria for multiple sclerosis: guideline for research protocols. Ann Neurol 13:227–231

    Google Scholar 

  17. Ringelstein EB, Krieger D, Hünermann B (1987) Evaluation by MRI of paraparesis and tetraparesis of undiagnosed aetiology. J Neurol 234:401–407

    Google Scholar 

  18. Schuller E, Benabdallah S, Sagar HJ, Reboul JAM, Tompe LC (1987) IgG synthesis within the central nervous system. Arch Neurol 44:600–604

    Google Scholar 

  19. Scotti G, Scialfa G, Biondi A, et al (1986) Magnetic resonance in multiple sclerosis. Neuroradiology 28:319–323

    Google Scholar 

  20. Steward JM, Houser OW, Baker HL, O'Brien PC, Rodriguez M (1987) Magnetic resonance imaging and clinical relationships in multiple sclerosis. Mayo Clin Proc 62:174–184

    Google Scholar 

  21. Swieten JC van, Hijdra A, Koudstaal PJ, Gijn J van (1990) Grading white matter lesions on CT and MRI: a simple scale. J Neurol Neurosurg Psychiatry 53:1080–1083

    Google Scholar 

  22. Twomey JA, Espir MLE (1980) Paroxysmal symptoms as the first manifestations of multiple sclerosis. J Neurol Neurosurg Psychiatry 43:296–304

    Google Scholar 

  23. Vaney C (1990) Schmerzen bei Multipler Sklerose. Schweiz Med Wochenschr 120:1959–1964

    Google Scholar 

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Uldry, PA., Regli, F. & Uské, A. Magnetic resonance imaging in patients with multiple sclerosis and spinal cord involvement: 28 cases. J Neurol 240, 41–45 (1993). https://doi.org/10.1007/BF00838445

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  • DOI: https://doi.org/10.1007/BF00838445

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