Skip to main content
Log in

Experimental studies on new liquid embolization mixtures (Histoacryl-Lipiodol, Histoacryl-Panthopaque)

  • Published:
CardioVascular and Interventional Radiology Aims and scope Submit manuscript

Abstract

In vitro measurements have proved that the polymerization time of n-butylcyanoacrylate (Histoacryl) can be delayed markedly and controlled by adding an oily radiopaque material. Our animal experiments have shown that a mixture of Histoacryl and Lipiodol ultrafluid at a 1∶3 ratio provided an optimal embolization material with good flow properties, polymerization time of approximately 7 sec and excellent contrast definition. This mixture may be handled easily, with a minimum of risk involved when used with a 40% glucose solution.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Athanasoulis CA (1980) Therapeutic applications of angiography. N Engl J Med 302:1117–1125, 1174–1179

    Article  PubMed  CAS  Google Scholar 

  2. Cromwell LD, Kerber CW (1979) Modification of cyanoacrylates for therapeutic embolization: Preliminary experience. AJR 132:799–801

    PubMed  CAS  Google Scholar 

  3. Dotter CT, Goldman ML, Rösch J (1975) Instant selective arterial occlusion with isobutyl-2-cyanoacrylate. Radiology

  4. Ekelund L, Mansson W, Olsson AM, Stigsson L (1979) Palliative embolization of arterial renal supply. Acta Radiol [Diagn] (Stockh) 20:323–336

    CAS  Google Scholar 

  5. Freeny PC, Bush WH, Kidd JR (1979) Transcatheter occlusive therapy of genitourinary abnormalities using isobutyl-2-cyanoacrylate (Bucrylate). AJR 133:647–656

    PubMed  CAS  Google Scholar 

  6. Freeny PC, Mennemeyer R, Kidd CR, Bush WH (1979) Long-term radiographic-pathologic follow-up of patients treated with visceral transcatheter occlusion using isobutyl-2-cyanoacrylate (Bucrylate). Radiology 132:51–60

    PubMed  CAS  Google Scholar 

  7. Günther R, Schubert U, Bohl J, Georgi M, Marberger M (1978) Transcatheter embolization of the kidney with butyl-2-cyanoacrylate: Experimental and clinical results. Cardiovasc Intervent Radiol 1:101–108

    Google Scholar 

  8. Lunderquist A, Börjesson B, Owman T, Bengmark S (1978) Isobutyl-2-cyanoacrylate (Bucrylate) in obliteration of gastric vein and esophageal varices. AJR 130:1–6

    PubMed  CAS  Google Scholar 

  9. McManus JFA (1948) The period acid routine applied to the kidney. Am J Pathol 24:643–653

    CAS  PubMed  Google Scholar 

  10. Movat HZ (1961) Silver impregnation methods for electron microscopy. Am J Clin Pathol 35:528

    PubMed  CAS  Google Scholar 

  11. Porstmann W, Münster W, Futh M, Krebs W, Schwozer A (1977) Die präoperative Embolisation der A. renalis bei Nierentumoren. Z Urol Nephrol 3:165–170

    Google Scholar 

  12. Skjennald A, Klevmark B, Stenwig JT (1980) Transcatheter embolization of renal artery with bucrylate in renal cardinoma. Acta Radiol [Diagn] (Stockh) 21:215–219

    CAS  Google Scholar 

  13. Zanetti PH, Sherman FE (1972) Experimental evaluation of tissue adhesive as an agent for the treatment of aneurysms and arteriovenous anomalies. J Neurosurg 36:72–79

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Stoesslein, F., Ditscherlein, G. & Romaniuk, P.A. Experimental studies on new liquid embolization mixtures (Histoacryl-Lipiodol, Histoacryl-Panthopaque). Cardiovasc Intervent Radiol 5, 264–267 (1982). https://doi.org/10.1007/BF02565409

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02565409

Key words

Navigation