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Long-term Outcome of Angioplasty Using a Wingspan Stent, Post-Stent Balloon Dilation and Aggressive Restenosis Management for Intracranial Arterial Stenosis

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A Correction to this article was published on 07 February 2020

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Abstract

Purpose

To investigate the long-term outcome of stent angioplasty for symptomatic severe intracranial artery stenosis.

Method

In this study 95 consecutive patients with intracranial atherosclerotic stenosis (>70%) underwent stent angioplasty using Wingspan stents. The primary endpoints were stroke or death within 30 days of the procedure and subsequent stroke attributed to the stented vessel. Disabling stroke was defined as stroke with a modified Rankin scale > 3. Secondary endpoints included transient ischemic attacks, contralateral stroke, nonstroke death, and other events. Patients underwent prestent balloon dilation with or without poststent balloon dilation, close restenosis follow-up, and selective retreatment, as required.

Result

The mean follow-up duration was 34.9 ± 23.3 months. Primary endpoint events occurred in 23% of the patients. The median infarction volume was 2.6 ml, and 11 (68%) of 16 infarctions were <5 ml in volume. Disabling stroke occurred in 3% of patients. The primary endpoint rates were 17.9% within 30 days and 2.1% from 30 days to 1 year. Secondary endpoint events occurred in 27.3% of the patients. Mean stenosis was reduced from 76.8 ± 6.1% to 7.5 ± 13.4%. Of 80 patients who underwent angiographic follow-up, 11 (14%) experienced restenosis (≥50%) and 7 (9%) exhibited restenosis-related symptoms of transient ischemic attack. The rate of symptomatic restenosis was significantly higher in patients who underwent prestent balloon dilation alone than in patients who underwent prestent and poststent balloon dilation (p = 0.016).

Conclusion

The postprocedural stroke rate was similar to that observed in the SAMMPRIS study. Symptomatic restenosis may be reduced by poststent dilation, close angiographic follow-up, and retreatment.

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Change history

  • 07 February 2020

    <Emphasis Type="Bold">Correction to:</Emphasis>

    <Emphasis Type="Bold">Clin Neuroradiol 2019</Emphasis>

    https://doi.org/10.1007/s00062-019-00793-1

    The original version of this article unfortunately contained some mistakes. The Institutional Review Board number was given wrongly in the Methods/Participants section and in the Compliance with ethical guidelines/Ethical

Abbreviations

DSA:

Digital subtraction angiography

PreB:

Prestent ballooning

PrePostB:

Prestent and poststent ballooning

TIA:

Transient ischemic attack

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Acknowledgements

This study was supported by Gangneung Asan Hospital research grant 2018-b09.

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Authors and Affiliations

  1. Department of Neurosurgery, Gangneung Asan Hospital, University of Ulsan College of Medicine, Bangdong-gil 38, Sacheon-myeon, 25440, Gangneung, Gangwon-do, Korea (Republic of)

    Seong-Cheol Park, Su Hee Cho, Moon-Kyu Kim & Seung-Hoon You

  2. Department of Neurology, Gangneung Asan Hospital, University of Ulsan College of Medicine, Gangneung, Korea (Republic of)

    Ji-Eun Kim, Woo-Young Jang, Moon-Kyu Lee & Kwang-Deog Jo

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Contributions

All authors made substantial contribution to the design of the study and analysis and interpretation of the data in this work. All authors drafted and/or critically revised the manuscript, provided final approval of the version to be published, and agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.

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Correspondence to Seung-Hoon You.

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Conflict of interest

S.-C. Park, S.H. Cho, M.-K. Kim, J.-E. Kim, W.-Y. Jang, M.-K. Lee, K.-D. Jo and S.-H. You declare that they have no competing interests.

Ethical standards

All procedures performed in studies involving human participants or on human tissue were in accordance with the ethical standards of the institutional and/or national research committee and with the 1975 Helsinki declaration and its later amendments or comparable ethical standards. Written patient consent was waived by the local ethics committee due to the retrospective design. Gangneung Asan Hospital Institutional Review Board (certification number: 010-3595-9706).

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Park, SC., Cho, S.H., Kim, MK. et al. Long-term Outcome of Angioplasty Using a Wingspan Stent, Post-Stent Balloon Dilation and Aggressive Restenosis Management for Intracranial Arterial Stenosis. Clin Neuroradiol 30, 159–169 (2020). https://doi.org/10.1007/s00062-019-00793-1

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