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Vein of Galen aneurysmal malformation: combined transvenous and transarterial method using a “kissing microcatheter technique”

  • Interventional Neuroradiology
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Abstract

Introduction

Vein of Galen aneurysmal malformation (VGAM) is a severe pediatric neurovascular disease. Children often present with congestive heart failure in the neonatal period. In the last decades, endovascular treatment became the first therapeutic option. The purpose of this study is to report our results in the treatment of VGAM with a combined transvenous and transarterial method in the last ten years.

Methods

In our cohort of 28 patients with VGAM, 22 patients were treated endovascularly between 1992 and 2010. In the last 10 years, a consecutive series of 14 children were treated with a combined transvenous and transarterial method. The therapeutic goal was immediate shunt reduction of the arteriovenous malformation, especially in the neonatal period. Closure of the fistulous connections was achieved by coiling using a combined transvenous and transarterial approach, called “kissing microcatheter technique”.

Results

Eight of 14 children presented in the neonatal period with severe congestive heart failure. The other six patients presented between the age of 2 and 17 months. One patient died due to a non-procedural complication in another hospital 2 years after the last treatment. Complete or >90% of angiographically confirmed closure of the malformation was documented in 11 of 14 patients. Normal or near-normal outcome was achieved in 9 of 13 surviving children, a non-favorable outcome was observed in four children. Control of heart failure was achieved in all patients.

Conclusion

Endovascular treatment of VGAM using a combined transvenous and transarterial method is a safe procedure with a low complication rate. The overall outcome can be improved, especially in the high-risk neonatal group with congestive heart failure.

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Acknowledgments

We thank Melania Arcadio and Armin Even for excellent technical support. Dan Meila wants to thank Professor Dr Alex Berenstein for encouragement and advice. The authors thank Annika Berg for editorial assistance in the preparation of this manuscript.

Conflict of interest

We declare that we have no conflict of interest.

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Correspondence to Dan Meila or Friedhelm Brassel.

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Meila, D., Hannak, R., Feldkamp, A. et al. Vein of Galen aneurysmal malformation: combined transvenous and transarterial method using a “kissing microcatheter technique”. Neuroradiology 54, 51–59 (2012). https://doi.org/10.1007/s00234-011-0860-4

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  • DOI: https://doi.org/10.1007/s00234-011-0860-4

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