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Diffusion tensor imaging reveals disease-specific deep cerebellar nuclear changes in cerebellar degeneration

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References

  1. Dimitrova A, Weber J, Redies C, Kindsvater K, Maschke M, Kolb FP, Forsting M, Diener HC, Timmann D (2002) MRI atlas of the human cerebellar nuclei. Neuroimage 17(1):240–255

    Article  CAS  PubMed  Google Scholar 

  2. Dimitrova A, Zeljko D, Schwarze F, Maschke M, Gerwig M, Frings M, Beck A, Aurich V, Forsting M, Timmann D (2006) Probabilistic 3D MRI atlas of the human cerebellar dentate/interposed nuclei. Neuroimage 30(1):12–25

    Article  CAS  PubMed  Google Scholar 

  3. Maschke M, Weber J, Dimitrova A, Bonnet U, Bohrenkämper J, Sturm S, Kindsvater K, Müller BW, Gastpar M, Diener HC, Forsting M, Timmann D (2004) Age-related changes of the dentate nuclei in normal adults as revealed by 3D fast low angle shot (FLASH) echo sequence magnetic resonance imaging. J Neurol 251(6):740–746

    Article  PubMed  Google Scholar 

  4. Landman BA, Du AX, Mayes WD, Prince JL, Ying SH (2007) Diffusion tensor imaging enables robust mapping of the deep cerebellar nuclei. Organization for Human Brain Mapping, Chicago, Illinois

    Google Scholar 

  5. Du AX, Landman BA, Zee DS, Prince JL, Ying SH (2007) Diffusion tensor imaging reveals disease-specific dentate nucleus changes in cerebellar degeneration. Organization for Human Brain Mapping, Chicago

    Google Scholar 

  6. Trouillas P, Takayanagi T, Hallett M, Currier RD, Subramony SH, Wessel K, Bryer A, Diener HC, Massaquoi S, Gomez CM, Coutinho P, Ben Hamida M, Campanella G, Filla A, Schut L, Timann D, Honnorat J, Nighoghossian N, Manyam B (1997) International cooperative ataxia rating scale for pharmacological assessment of the cerebellar syndrome. The Ataxia Neuropharmacology Committee of the world federation of neurology. J Neurol Sci 145(2):205–211

    Article  CAS  PubMed  Google Scholar 

  7. McAuliffe MJ, Lalonde FM, McGarry D, Gandler W, Csaky K, Trus BL (2001) Medical image processing, analysis, and visualization in clinical research. Proceedings of the 14th IEEE symposium on computer-based medical systems, 381–386

  8. Duvernoy HM (1995) The human brain stem and cerebellum. Springer, Berlin

    Google Scholar 

  9. Murata Y, Kawakami H, Yamaguchi S, Nishimura M, Kohriyama T, Ishizaki F, Matsuyama Z, Mimori Y, Nakamura S (1998) Characteristic magnetic resonance imaging findings in spinocerebellar ataxia 6. Arch Neurol 55(10):1348–1352

    Article  CAS  PubMed  Google Scholar 

  10. Tashiro H, Suzuki SO, Hitotsumatsu T, Iwaki T (1999) An autopsy case of spinocerebellar ataxia type 6 with mental symptoms of schizophrenia and dementia. Clin Neuropathol 18(4):198–204

    CAS  PubMed  Google Scholar 

  11. Schulz JB, Borkert J, Wolf S, Schmitz-Hübsch T, Rakowicz M, Mariotti C, Schoels L, Timmann D, van de Warrenburg B, Dürr A, Pandolfo M, Kang JS, Mandly AG, Nägele T, Grisoli M, Boguslawska R, Bauer P, Klockgether T, Hauser TK (2010) Visualization, quantification and correlation of brain atrophy with clinical symptoms in spinocerebellar ataxia types 1, 3 and 6. Neuroimage 49:158–168

    Article  PubMed  Google Scholar 

Download references

Acknowledgments

This work was supported by the Arnold-Chiari Foundation, the Robin Zee Fund, the Dana Foundation Program for Brain and Immuno-Imaging, the National Organization for Rare Disorders, the National Alliance for Research on Schizophrenia and Depression, the Office of Naval Research NDSEGF (Landman), and the following NIH grants: K23EY015802, M01-RR00052, R21NS059830, R01NS054255, and R01NS056307. Special acknowledgments to Wade Mayes, Alex H. Sinofsky, and Katherine K. Loya for their invaluable contributions to this work.

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Authors and Affiliations

  1. Department of Pathology, The Johns Hopkins University School of Medicine, 2-210, 600 N. Wolfe St., Baltimore, MD, 21287, USA

    Annie X. Du, Jennifer L. Cuzzocreo, David S. Zee & Sarah H. Ying

  2. 324B Clark Hall, 3400 North Charles Street, Baltimore, MD, 21218, USA

    Bennett A. Landman

  3. 201B Clark Hall, 3400 North Charles Street, Baltimore, MD, 21218, USA

    Jerry L. Prince

Authors
  1. Annie X. Du
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  2. Jennifer L. Cuzzocreo
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  3. Bennett A. Landman
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  4. David S. Zee
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  5. Jerry L. Prince
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  6. Sarah H. Ying
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Correspondence to Sarah H. Ying.

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Du, A.X., Cuzzocreo, J.L., Landman, B.A. et al. Diffusion tensor imaging reveals disease-specific deep cerebellar nuclear changes in cerebellar degeneration. J Neurol 257, 1406–1408 (2010). https://doi.org/10.1007/s00415-010-5523-6

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  • DOI: https://doi.org/10.1007/s00415-010-5523-6

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