Clinical study
Mouth and genital ulcers with inflamed cartilage: MAGIC syndrome. Five patients with features of relapsing polychondritis and behçet's disease☆

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Abstract

Five patients with features of coexistent relapsing polychondritis and Behçet's disease are described. Review of the literature supports the overlap of the clinical manifestations of these two conditions. A common immunologic abnormality is likely, and elastin is cited as a possible target antigen. The “mouth and genital ulcers with inflamed cartilage (MAGIC) syndrome” is the proposed name for this entity.

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    ☆

    This work was supported by National Institutes of Health Training Grant AM07062-09, National Institutes of Health Division of Research Resources Grant RR-00827, and a Lupus Foundation grant.

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