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Enhanced expression of the calcium-sensing receptor in reactive astrocytes following ischemic injury in vivo and in vitro
2016, Journal of the Neurological SciencesUpregulated vimentin suggests new areas of neurodegeneration in a model of an alcohol use disorder
2011, NeuroscienceCitation Excerpt :These data support that vimentin upregulation is due to cell death rather than ethanol withdrawal-induced seizures. Vimentin upregulation is thought to be indicative of permanent damage (Petito et al., 1990) and a more sensitive indicator of necrosis than GFAP upregulation (Schmidt-Kastner et al., 1990). Accordingly, following binge ethanol exposure, vimentin is upregulated in many of the same regions that show neurodegeneration according to de Olmos cupric silver stain (Collins et al., 1996; Crews et al., 2000; Obernier et al., 2002a, b).
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