Invited reviewRecent advances on neuronal caspases in development and neurodegeneration
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Keywords
Apoptosis
Programmed cell death
bcl-2 proteins
Inhibitor of apoptosis proteins (IAPs)
Caspase inhibitors
Caspase substrates
CED-3
CED-4
CED-9
Apoptosis associated factors (Apafs)
Abbreviations
IAPs, inhibitory associated proteins include
NAIP, ‘neuronal apoptosis inhibitory protein’ and survivin
IERG, immediate early response genes
ICAD, inhibitor of caspase associated DNase
PARP, poly(ADP-ribose) polymerase, a DNA repair enzyme
DD, death domain
DED, death effector domain
CARD, caspase associated recruitment domain
Apaf, apoptosis associated factor
PCD, programmed cell death
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