Elsevier

Clinical Radiology

Volume 57, Issue 3, March 2002, Pages 219-225
Clinical Radiology

Regular Article
Diffusion MR Imaging in Glioma: Does It Have Any Role in the Pre-operation Determination of Grading of Glioma?

https://doi.org/10.1053/crad.2001.0741Get rights and content

Abstract

AIM: To investigate the role of the diffusion MR weighted sequence in the pre-operative grading of gliomas, and its application in defining the different components of these tumours. MATERIALS AND METHODS: Seventeen patients with gliomas (eight high grade, nine low grade) had diffusion weighted imaging. Apparent diffusion coefficients (ADCs) of different components of tumours were measured. RESULTS: ADC of the cystic portion of the tumour was significantly higher than ADCs of the enhanced tumour, non-enhanced tumour and perifocal oedema (P < 0.01). No significant difference in ADC values between low grade and high grade glioma (P > 0.7) was found nor was there any difference between oligoglioma and non-oligoglioma (P > 0.29). CONCLUSION: ADC value was useful to differentiate the cystic from the solid components of the tumours. However, it was not useful in pre-operative grading of glioma. Lam, W. W. M., Poon, W. S. and Metreweli, C. (2002). Clinical Radiology57, 219–225.

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Author for correspondence and guarantor of study: W. W. M. Lam, Department of Diagnostic Radiology and Organ Imaging, Faculty of Medicine, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong. Fax: +852 2636 0012; E-mail: [email protected]

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