Semin Neurol 1997; 17(1): 39-44
DOI: 10.1055/s-2008-1040911
© 1997 by Thieme Medical Publishers, Inc.

Lyme Disease in Children

Eugene D. Shapiro, Elyse G. Seltzer
  • Departments of Pediatrics, Epidemiology (E.D.S.), Medicine (E.G.S.), and the Children's Clinical Research Center (E.D.S), Yale University School of Medicine, New Haven, Connecticut
Further Information

Publication History

Publication Date:
19 March 2008 (online)

ABSTRACT

Neurologic manifestations of Lyme disease are common in children, among whom the incidence of Lyme disease is higher than among adults. Cranioneuropathies, in particular palsy of the facial nerve, occur in approximately 3-5% of children with Lyme disease, followed in frequency by meningitis (1% of symptomatic children). Children with only non-specific symptoms such as headache, arthralgia or fatigue commonly are misdiagnosed as having Lyme disease. Although such non-specific symptoms often accompany more specific signs and symptoms (e.g., erythema migrans, arthritis) in children with Lyme disease, very rarely are non-specific symptoms the sole manifestation of Lyme disease. A number of carefully conducted follow-up studies have indicated that the prognosis is excellent for children with Lyme disease who have been treated with standard antimicrobial regimens.

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