Cerebral Venous Sinus Thrombosis as a Presentation of COVID-19
  • Christopher Hughes
    Betsi Cadwaladr University Health Board, Bangor, Wales, UK
  • Tom Nichols
    Betsi Cadwaladr University Health Board, Bangor, Wales, UK
  • Martin Pike
    Betsi Cadwaladr University Health Board, Bangor, Wales, UK
  • Christian Subbe
    Betsi Cadwaladr University Health Board, Bangor, Wales, UK
  • Salah Elghenzai
    Betsi Cadwaladr University Health Board, Bangor, Wales, UK

Keywords

COVID-19, cerebral venous sinus thrombosis, anticoagulation, stroke

Abstract

Coronavirus disease 19 (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). We describe the case of a 59-year-old man who presented with headache, hypertension and a single episode of fever with no other symptoms. He subsequently developed unilateral weakness. Computer tomography identified a cerebral venous sinus thrombosis (CVST). A subsequent test for COVID-19 was positive. This is the first report of CVST as a presenting symptom of COVID-19 infection.

VIEW THE ENTIRE ARTICLE

References

  • Huang C, Wang Y, Li X, Ren L, Zhao J, Hu Y, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet 2020;395(10223):497–506.

  • Long B, Brady WJ, Koyfman A, Gottlieb M. Cardiovascular complications in COVID-19. Am J Emerg Med 2020 Apr 18. pii: S0735-6757(20)30277-1. doi: 10.1016/j.ajem.2020.04.048 [Epub ahead of print].

  • Kochi AN, Tagliari AP, Forleo GB, Fassini GM, Tondo C. Cardiac and arrhythmic complications in patients with COVID-19. J Cardiovasc Electrophysiol 2020 Apr 9. doi: 10.1111/jce.14479 [Epub ahead of print].

  • Marietta M, Ageno W, Artoni A, De Candia E, Gresele P, Marchetti M, et al. COVID-19 and haemostasis: a position paper from Italian Society on Thrombosis and Haemostasis (SISET). Blood Transfus 2020 Apr 8. doi: 10.2450/2020.0083-20 [Epub ahead of print].

  • Bikdeli B, Madhavan MV, Jimenez D, Chuich T, Dreyfus I, Driggin E, et al. COVID-19 and thrombotic or thromboembolic disease: implications for prevention, antithrombotic therapy, and follow-up. J Am Coll Cardiol 2020 Apr 15. pii: S0735-1097(20)35008-7. doi: 10.1016/j.jacc.2020.04.031 [Epub ahead of print].

  • Song JC, Wang G, Zhang W, Zhang Y, Li WQ, Zhou Z, et al. Chinese expert consensus on diagnosis and treatment of coagulation dysfunction in COVID-19. Mil Med Res 2020;7(1):19.

  • Zhai Z, Li C, Chen Y, Gerotziafas G, Zhang Z, Wan J, et al. Prevention and treatment of venous thromboembolism associated with coronavirus disease 2019 infection: a consensus statement before guidelines. Thromb Haemost 2020 Apr 21. doi: 10.1055/s-0040-1710019 [Epub ahead of print].

  • Casini A, Alberio L, Angelillo-Scherrer A, Fontana P, Gerber B, Graf L, et al. Thromboprophylaxis and laboratory monitoring for in-hospital patients with COVID-19 - a Swiss consensus statement by the Working Party Hemostasis. Swiss Med Wkly 2020;150:w20247.

  • John Hopkins University. COVID-19 Case Tracker 2020. Available from: https://coronavirus.jhu.edu (accessed 28 April 2020).

  • Magdi M, Rahil A. Severe immune thrombocytopenia complicated by intracerebral haemorrhage associated with coronavirus infection: a case report and literature review. Eur J Case Rep Intern Med 2019;6(7):001155.

  • Giannis D, Ziogas IA, Gianni P. Coagulation disorders in coronavirus infected patients: COVID-19, SARS-CoV-1, MERS-CoV and lessons from the past. J Clin Virol 2020;127:104362.

  • Alvis-Miranda HR, Milena Castellar-Leones S, Alcala-Cerra G, Rafael Moscote-Salazar L. Cerebral sinus venous thrombosis. J Neurosci Rural Pract 2013;4(4):427–438.
  • Views: 5192
    HTML downloads: 639
    PDF downloads: 1818


    Published: 2020-04-29
    Issue: 2020: Vol 7 No 5 (view)


    How to cite:
    1.
    Hughes C, Nichols T, Pike M, Subbe C, Elghenzai S. Cerebral Venous Sinus Thrombosis as a Presentation of COVID-19. EJCRIM 2020;7 doi:10.12890/2020_001691.