Abstract
Advances in developmental biology combined with progress in human genetics are helping us decipher how the craniofacial region develops and how the consequences of misdirected development result in malformation. This review describes the molecular etiology of a number of craniofacial developmental anomalies. The more common craniofacial anomalies cleft lip and palate and craniosynostosis, as well as cleidocranial dysplasia, hemifacial microsomia, holoprosencephaly, enlarged parietal foramina, Treacher Collins syndrome and cherubism are discussed.
Keywords: Cleft lip and palate, craniosynostosis, holoprosencephaly, hemifacial microsomia, Treacher Collins syndrome, cleidocranial dysplasia, parietal foramina, cherubism, craniofacial development
Current Molecular Medicine
Title: Craniofacial Anomalies: From Development to Molecular Pathogenesis
Volume: 5 Issue: 7
Author(s): David P.C. Rice
Affiliation:
Keywords: Cleft lip and palate, craniosynostosis, holoprosencephaly, hemifacial microsomia, Treacher Collins syndrome, cleidocranial dysplasia, parietal foramina, cherubism, craniofacial development
Abstract: Advances in developmental biology combined with progress in human genetics are helping us decipher how the craniofacial region develops and how the consequences of misdirected development result in malformation. This review describes the molecular etiology of a number of craniofacial developmental anomalies. The more common craniofacial anomalies cleft lip and palate and craniosynostosis, as well as cleidocranial dysplasia, hemifacial microsomia, holoprosencephaly, enlarged parietal foramina, Treacher Collins syndrome and cherubism are discussed.
Export Options
About this article
Cite this article as:
Rice P.C. David, Craniofacial Anomalies: From Development to Molecular Pathogenesis, Current Molecular Medicine 2005; 5 (7) . https://dx.doi.org/10.2174/156652405774641043
DOI https://dx.doi.org/10.2174/156652405774641043 |
Print ISSN 1566-5240 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5666 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Recent Patents on Biomedical Devices and Nanomaterials for Hyperthermal Therapy of Cancer
Recent Patents on Nanomedicine Genetic Variation and Atherosclerosis
Current Genomics Update on the Imaging Techniques in the Diagnosis of Diabetic Retinopathy
Current Diabetes Reviews The Ignored Role of Intraoperative Hypotension in Producing Postoperative Acute Kidney Injury-An Obligatory Appeal for More Preventative Nephrology
Current Hypertension Reviews MicroRNAs in Peripheral Artery Disease
Current Topics in Medicinal Chemistry Thrombolytic Treatment of Cardiac Myxoma-Induced Ischemic Stroke: A Review
Current Drug Safety Progress in the Development of Matrix Metalloproteinase Inhibitors
Current Medicinal Chemistry Leukocytes in Diabetic Retinopathy
Current Diabetes Reviews The Role of Autophagy in Subarachnoid Hemorrhage: An Update
Current Neuropharmacology Marfan Syndrome and Related Heritable Thoracic Aortic Aneurysms and Dissections
Current Pharmaceutical Design Nanomaterial Based Approaches for the Diagnosis and Therapy of Cardiovascular Diseases
Current Pharmaceutical Design Effects of Acute and Chronic Biomechanical Strain on Human Cerebral Endothelial Cells in Altering their Proteome Profile
Current Proteomics Cystatin C: An Emerging Biomarker in Cardiovascular Disease
Current Topics in Medicinal Chemistry Immunosuppressive Treatments in Acute Myocardial Infarction and Stroke
Current Pharmaceutical Biotechnology The Stroke-Induced Blood-Brain Barrier Disruption: Current Progress of Inspection Technique, Mechanism, and Therapeutic Target
Current Neuropharmacology MMP-9 Inhibitors in the Brain: Can Old Bullets Shoot New Targets?
Current Pharmaceutical Design Current Understanding of the Molecular Mechanism between Hemodynamic- Induced Intracranial Aneurysm and Inflammation
Current Protein & Peptide Science Cyano Acrylate Polymers in Medical Applications
Recent Patents on Materials Science Current Indications for Implantable Cardioverter Defibrillators in Non-Ischemic Cardiomyopathies and Channelopathies
Reviews on Recent Clinical Trials Blood Pressure and White Matter Lesions in Patients with Vascular Disease: The SMART-MR Study
Current Neurovascular Research