Abstract
This article reviews the current knowledge with regard to neurotoxicity of conventional radiation, including recent understanding of the pathophysiology, molecular biology, diagnostic evaluation and clinical presentations, as well as proposed treatment modalities and possible protective agents.
MeSH terms
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Brain / pathology
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Brain / radiation effects*
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Central Nervous System Neoplasms / pathology
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Central Nervous System Neoplasms / radiotherapy*
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Cranial Irradiation / adverse effects*
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Diagnosis, Differential
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Humans
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Magnetic Resonance Imaging
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Prognosis
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Radiation Injuries / diagnosis*
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Radiation Injuries / pathology
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Radiation Injuries / therapy
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Radiotherapy Dosage
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Spinal Cord / pathology
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Spinal Cord / radiation effects*