Abstract
Bilateral symmetric striopallidodentate calcinosis, also known as Fahr's disease, is characterized by bilateral calcifications of the basal ganglia, thalami, dentate nuclei of the cerebellum, and the white matter of the cerebral hemisphere. Intracranial calcifications are easily visible as high-density areas on computed tomographic images. On magnetic resonance images, the calcifications exhibit different signal intensities. The differences in signal intensity are thought to be related to the stage of the disease, differences in calcium metabolism, and the volume of the calcium deposit. The moderate reduction of cerebral blood flow in bilateral thalami was also identified using brain SPECT.
MeSH terms
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Aged
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Basal Ganglia Diseases / complications
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Basal Ganglia Diseases / diagnostic imaging
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Basal Ganglia Diseases / pathology
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Brain Diseases / complications
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Brain Diseases / diagnostic imaging*
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Brain Diseases / pathology
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Calcinosis / complications
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Calcinosis / diagnostic imaging*
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Calcinosis / pathology
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Cerebellar Diseases / complications
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Cerebellar Diseases / diagnostic imaging
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Cerebellar Diseases / pathology
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Cysteine / analogs & derivatives*
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Dysarthria / etiology
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Gait Ataxia / etiology
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Humans
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Male
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Occipital Lobe / diagnostic imaging
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Organotechnetium Compounds*
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Paralysis / etiology
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Radiography
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Radiopharmaceuticals
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Thalamic Diseases / complications
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Thalamic Diseases / diagnostic imaging
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Thalamic Diseases / pathology
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Tomography, Emission-Computed, Single-Photon*
Substances
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Organotechnetium Compounds
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Radiopharmaceuticals
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technetium Tc 99m bicisate
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Cysteine