Pseudotumor cerebri

Curr Opin Ophthalmol. 2003 Dec;14(6):364-70. doi: 10.1097/00055735-200312000-00008.

Abstract

Purpose of review: To discuss the current standard in diagnosis and treatment of pseudotumor cerebri (PTC), the syndrome of increased intracranial pressure without a brain tumor. Since PTC is a diagnosis of exclusion, the differential diagnostic work-up is of special importance.

Recent findings: Modern imaging techniques have facilitated the differential diagnosis of PTC. Various therapeutic options are available to prevent irreversible visual loss. New treatment modalities are being explored, but the standard therapy has undergone little change in the past years.

Summary: PTC, a potentially blinding disease, most commonly manifests with headache and slightly blurred vision due to papilledema. This review seeks to present a methodical approach to its diagnosis and treatment.

Publication types

  • Review

MeSH terms

  • Acetazolamide / therapeutic use
  • Adrenal Cortex Hormones / therapeutic use
  • Carbonic Anhydrase Inhibitors / therapeutic use
  • Diagnosis, Differential
  • Humans
  • Magnetic Resonance Angiography
  • Magnetic Resonance Imaging
  • Pseudotumor Cerebri / diagnosis*
  • Pseudotumor Cerebri / therapy*
  • Spinal Puncture
  • Weight Loss

Substances

  • Adrenal Cortex Hormones
  • Carbonic Anhydrase Inhibitors
  • Acetazolamide