Eosinophilic angiocentric fibrosis in a patient with nasal obstruction

Ear Nose Throat J. 2004 Mar;83(3):183-4, 186.

Abstract

Eosinophilic angiocentric fibrosis (EAF) is a rare clinicopathologic entity that usually affects the upper respiratory tract. We describe the case of a 45-year-old man with nasal obstruction caused by EAF. His lesion featured the distinct radiologic and histopathologic characteristics of EAF, which include an onionskin and whorled fibrosis that surrounds the blood vessels and an inflammatory infiltrate that is predominated by eosinophils. The etiology of EAF remains unknown. Given our increasing knowledge of this rare entity, reports of EAF may appear more frequently in the future.

Publication types

  • Case Reports

MeSH terms

  • Eosinophilia / complications
  • Eosinophilia / pathology*
  • Fibrosis / complications
  • Fibrosis / diagnostic imaging
  • Fibrosis / pathology*
  • Humans
  • Immunohistochemistry
  • Male
  • Middle Aged
  • Nasal Obstruction / diagnostic imaging
  • Nasal Obstruction / etiology*
  • Nasal Obstruction / pathology*
  • Tomography, X-Ray Computed