Clinical features and diagnosis of primary central nervous system lymphoma

April Fitzsimmons; Kristen Upchurch; Tracy Batchelor

doi:10.1016/j.hoc.2005.05.009

Clinical features and diagnosis of primary central nervous system lymphoma

Hematol Oncol Clin North Am. 2005 Aug;19(4):689-703, vii. doi: 10.1016/j.hoc.2005.05.009.

Authors

April Fitzsimmons¹, Kristen Upchurch, Tracy Batchelor

Affiliation

¹ Stephen E. and Catherine Pappas Center for Neuro-Oncology, Yawkey 9E, Massachusetts General Hospital/Harvard Medical School, 55 Fruit Street, Boston, MA 02114, USA.

PMID: 16083830
DOI: 10.1016/j.hoc.2005.05.009

Abstract

This article reviews the clinical features of primary central nervous system lymphoma (PCNSL) in immunocompetent and immunocompromised patients. Clinical presentation, differential diagnosis, diagnostic testing, and staging evaluation in both immunocompetent and AIDS patients who have PCNSL are discussed. The differing role of biopsy in these two populations also is addressed.

Publication types

Review

MeSH terms

Central Nervous System Neoplasms / diagnosis*
Central Nervous System Neoplasms / therapy
Humans
Lymphoma / diagnosis*
Lymphoma / therapy
Neoplasm Staging