A multivariate analysis of the factors predicting hearing outcome after surgery for cholesteatoma in children

J Laryngol Otol. 2006 Nov;120(11):908-13. doi: 10.1017/S0022215106002179. Epub 2006 Jul 24.

Abstract

Objective: To explore factors influencing hearing outcomes in children treated by canal wall up (CWU) and canal wall down (CWD) mastoid surgery.

Methods: Retrospective cohort study including three units in Bristol and Bath, UK. Ninety consecutive children underwent cholesteatoma mastoid surgery, with the first procedure between 1998 and 2001; minimum follow up was three disease-free years.

Results: The CWU and CWD cohorts significantly differed in pre-operative stage and hearing. After disease eradication, air conduction (AC) thresholds changed by +4.0 dB (95 per cent confidence intervals (95% CI) -2.0, 10.1) in the CWD group and -5.3 dB (95% CI -9.3, 1.3) in the CWU group (p=0.029). Using multiple linear regression to account for cohort differences, AC thresholds were increased by: pre-operative AC threshold (p<0.0001), initial ossicular stage (p=0.013), and CWD-surgery (p=0.005).

Conclusion: Disease-free hearing was better with CWU-surgery, less initial ossicular damage, and better pre-operative hearing. Worse initial disease increased the likelihood of CWD surgery. Wider use of ossiculoplasty in the CWU cohort (51 per cent vs 5 per cent) may partially explain the superior results.

Publication types

  • Multicenter Study

MeSH terms

  • Adolescent
  • Child
  • Child, Preschool
  • Cholesteatoma, Middle Ear / complications
  • Cholesteatoma, Middle Ear / surgery*
  • Cohort Studies
  • England
  • Female
  • Hearing Disorders / etiology
  • Hearing*
  • Humans
  • Male
  • Mastoid / surgery*
  • Multivariate Analysis
  • Otologic Surgical Procedures / methods
  • Retrospective Studies
  • Treatment Outcome