Several distinct clinical syndromes can accompany low back pain in patients with lumbar spine abnormality. Developmental factors and any superimposed degenerative changes determine the size and configuration of the spinal canal, lateral recess, and neural foramen, and can affect the nerve roots. Somatic or referred pain may develop depending on the involved anatomic site and underlying pathology. Many times, but not always, MR imaging findings correlate with the clinical presentation. Combined analysis of the imaging and clinical findings may provide a more accurate and concise approach to the patient with low back pain.