Eosinophilic angiocentric fibrosis of the sinonasal tract

Ann Diagn Pathol. 2008 Aug;12(4):267-270. doi: 10.1016/j.anndiagpath.2007.02.002. Epub 2007 Oct 3.

Abstract

Eosinophilic angiocentric fibrosis (EAF) is an uncommon inflammatory fibrosing lesion of the upper respiratory tract and orbit that occurs mainly in young to middle-aged women. The etiology of EAF is unknown. To our knowledge, approximately 28 cases have been previously reported in the English literature. We report here 3 additional cases of EAF of the sinonasal tract; 2 in women aged 19 and 31 years, and 1 in a man aged 49 years. The 19-year-old woman is the youngest patient with EAF ever described. The patients presented with a nasal cavity mass, face pain, or nasal obstructive symptoms of long duration.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Eosinophilia / pathology*
  • Facial Pain / pathology
  • Female
  • Fibrosis
  • Humans
  • Male
  • Maxillary Sinus / pathology
  • Middle Aged
  • Nasal Cavity / pathology
  • Nasal Obstruction / etiology*
  • Nasal Obstruction / pathology*
  • Nasal Septum / pathology