Balloon-assisted Onyx embolization of cerebral single-channel pial arteriovenous fistulas

J Neurosurg Pediatr. 2011 Jun;7(6):637-42. doi: 10.3171/2011.4.PEDS10577.

Abstract

Object: Pial arteriovenous fistulas (AVFs) of the brain are rare vascular malformations associated with significant risks of hemorrhage and neurological deficit. Depending on their location and high-flow dynamics, these lesions can present treatment challenges for both endovascular and open cerebrovascular surgeons. The authors describe a novel endovascular treatment strategy that was used successfully to treat 2 pediatric patients with a pial AVF, and they discuss the technical nuances specific to their treatment strategy.

Methods: A single-channel high-flow pial AVF was diagnosed in 2 male patients (6 and 17 years of age). Both patients were treated with endovascular flow arrest using a highly conformable balloon followed by Onyx infusion for definitive closure of the fistula.

Results: Neither patient suffered a complication as a result of the procedure. At the 6-month follow-up in both cases, the simple discontinuation of blood flow had resulted in durable obliteration of the fistula and stable or improved neurological function.

Conclusions: Onyx can be delivered successfully into high-flow lesions after flow arrest to allow a minimally invasive and durable treatment for pial AVFs.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Arteriovenous Fistula / diagnostic imaging
  • Arteriovenous Fistula / therapy*
  • Balloon Occlusion / instrumentation
  • Balloon Occlusion / methods*
  • Child
  • Embolization, Therapeutic / instrumentation
  • Embolization, Therapeutic / methods*
  • Follow-Up Studies
  • Humans
  • Intracranial Arteriovenous Malformations / diagnostic imaging
  • Intracranial Arteriovenous Malformations / therapy*
  • Magnetic Resonance Angiography
  • Male
  • Pia Mater / blood supply*
  • Polyvinyls / administration & dosage*
  • Tomography, X-Ray Computed
  • Treatment Outcome

Substances

  • Polyvinyls
  • ethylene-vinyl alcohol copolymer