Quantitative diffusion-weighted magnetic resonance imaging in the evaluation of parotid gland masses: a study with histopathological correlation

Clin Imaging. 2013 Mar-Apr;37(2):232-8. doi: 10.1016/j.clinimag.2012.04.025. Epub 2012 Jun 8.

Abstract

We evaluated the quantitative diffusion-weighted magnetic resonance imaging (DW-MRI) for parotid masses. Seventy-five patients with 81 focal parotid masses were included. Following DW-MRI, 73 masses underwent surgical biopsy/resection, 6 underwent ultrasonography-guided fine-needle aspiration, and 2 underwent both procedures. The mean apparent diffusion coefficient (ADC) of benign tumors (n=49, 1.72×10(-3) mm(2)/s) was higher than that of malignant tumors (n=32, 1.05×10(-3) mm(2)/s) (P<.001). ADC was 2.15×10(-3) mm(2)/s for pleomorphic adenomas, which was higher than that for other tumors (P<.001 for all). ADC cutoff was 1.315 for distinguishing between pleomorphic adenomas and others including malignant tumors. Therefore, DW-MRI may be useful for distinguishing between pleomorphic adenomas and other parotid masses.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Chi-Square Distribution
  • Child
  • Diagnosis, Differential
  • Diffusion Magnetic Resonance Imaging / methods*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Parotid Gland / pathology*
  • Parotid Neoplasms / diagnosis*
  • Parotid Neoplasms / pathology
  • ROC Curve
  • Sensitivity and Specificity
  • Statistics, Nonparametric