Neuroimaging of white matter injury, intraventricular and cerebellar hemorrhage

Clin Perinatol. 2014 Mar;41(1):69-82. doi: 10.1016/j.clp.2013.09.005. Epub 2013 Dec 17.

Abstract

White matter injury and hemorrhage are common findings in extremely preterm infants. Large hemorrhages and extensive cystic lesions are identified with cranial ultrasound. MRI, which is more sensitive, is especially useful in the identification of small intraventricular hemorrhage; cerebellar hemorrhage; punctate lesion in the white matter and cerebellum; and diffuse, noncystic white matter injury. Imaging sequences such as diffusion-weighted, diffusion tensor, and susceptibility weighted imaging may improve recognition and prediction of outcome. These techniques improve understanding of the underlying pathophysiology of white matter injury and its effects on brain development and neurodevelopmental outcome.

Keywords: Cerebellar hemorrhage; IVH; Imaging; MRI; PWML; White matter injury; cPVL.

Publication types

  • Review

MeSH terms

  • Cerebellar Diseases / diagnostic imaging
  • Cerebellar Diseases / pathology*
  • Cerebral Hemorrhage / diagnostic imaging
  • Cerebral Hemorrhage / pathology*
  • Cerebral Ventricles / diagnostic imaging
  • Cerebral Ventricles / pathology*
  • Echoencephalography / methods
  • Humans
  • Infant, Newborn
  • Infant, Premature
  • Infant, Premature, Diseases / diagnostic imaging
  • Infant, Premature, Diseases / pathology
  • Intracranial Hemorrhages / diagnostic imaging
  • Intracranial Hemorrhages / pathology
  • Leukomalacia, Periventricular / diagnostic imaging
  • Leukomalacia, Periventricular / pathology*
  • Magnetic Resonance Imaging / methods
  • Nerve Fibers, Myelinated / diagnostic imaging
  • Nerve Fibers, Myelinated / pathology*
  • Neuroimaging / methods*