Postencephalitic parkinsonism and selective involvement of substantia nigra in childhood

Ibtihel Rebai; Hanene Ben Rhouma; Ichraf Kraoua; Hedia Klaa; Aida Rouissi; Ilhem Ben Youssef-Turki; Neziha Gouider-Khouja

doi:10.1016/j.braindev.2014.03.009

Postencephalitic parkinsonism and selective involvement of substantia nigra in childhood

Brain Dev. 2015 Jan;37(1):153-7. doi: 10.1016/j.braindev.2014.03.009. Epub 2014 Apr 16.

Authors

Ibtihel Rebai¹, Hanene Ben Rhouma², Ichraf Kraoua², Hedia Klaa², Aida Rouissi², Ilhem Ben Youssef-Turki², Neziha Gouider-Khouja²

Affiliations

¹ Research Unit 06/11 and Department of Child and Adolescent Neurology, National Institute Mongi Ben Hmida of Neurology, Tunis, Tunisia. Electronic address: ibtihelrebai@yahoo.fr.
² Research Unit 06/11 and Department of Child and Adolescent Neurology, National Institute Mongi Ben Hmida of Neurology, Tunis, Tunisia.

PMID: 24745788
DOI: 10.1016/j.braindev.2014.03.009

Abstract

Parkinsonism is a rare complication of encephalitis in childhood. Association to an isolated involvement of substantia nigra is exceptional. Mechanisms of nigral cells neurotropism remain hypothetic. We report on three children presenting with postencephalitic parkinsonism and selective involvement of substantia nigra, with literature review and we discuss pathogenic mechanisms.

Keywords: Childhood; Encephalitis; MRI; Parkinsonism; Substantia nigra.

Publication types

Case Reports
Review

MeSH terms

Child
Child, Preschool
Encephalitis / complications*
Encephalitis / pathology
Encephalitis / physiopathology
Female
Humans
Magnetic Resonance Imaging
Male
Parkinsonian Disorders / etiology*
Parkinsonian Disorders / pathology
Parkinsonian Disorders / physiopathology
Substantia Nigra / pathology*