A review of cavernous malformations with trigeminal neuralgia

Clin Neurol Neurosurg. 2014 Oct:125:151-4. doi: 10.1016/j.clineuro.2014.07.025. Epub 2014 Jul 30.

Abstract

Cavernous malformation with trigeminal neuralgia is relatively rare; only 10 cases have been reported. In deciding treatment strategies, it is helpful to classify cavernous malformation according to its origin, as follows: in the Gasserian ganglion (Type G); between the cisternal and intra-axial portions of the trigeminal nerve root (Type C); in the intra-axial trigeminal nerve root in the pons (Type P); or in the spinal tract of the trigeminal nerve root (Type S). A 62-year-old male presented with left trigeminal neuralgia (V2 area) and left facial hypoesthesia. Imaging studies revealed a cerebellopontine angle mass lesion with characteristics of a cavernous malformation and evidence of hemorrhage. The lesion was completely removed via a left anterior transpetrosal approach. The mass was attached to the trigeminal nerve root; it was located between the cisternal and intra-axial portions of the nerve root, and feeding off microvessels from the trigeminal nerve vascular plexus. Histological examination confirmed a cavernous malformation. In this case, the cavernous malformation was Type C. We review cases of cavernous malformation with trigeminal neuralgia and discuss therapeutic strategies according to the area of origin.

Keywords: Anterior transpetrosal approach; Cavernous malformation; Operative approach; Pons; Trigeminal neuralgia.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Cerebellopontine Angle / pathology
  • Cerebellopontine Angle / surgery*
  • Humans
  • Intracranial Arteriovenous Malformations / diagnosis
  • Intracranial Arteriovenous Malformations / pathology
  • Intracranial Arteriovenous Malformations / surgery*
  • Male
  • Middle Aged
  • Neurosurgical Procedures*
  • Treatment Outcome
  • Trigeminal Nerve / pathology
  • Trigeminal Nerve / surgery*
  • Trigeminal Neuralgia / diagnosis
  • Trigeminal Neuralgia / pathology
  • Trigeminal Neuralgia / surgery*