Dose reduction in cone-beam CT scanning for intracranial stent deployment before coil embolization of intracranial wide-neck aneurysms

Interv Neuroradiol. 2016 Aug;22(4):420-5. doi: 10.1177/1591019916632489. Epub 2016 Feb 24.

Abstract

Purpose: Flat panel detector (FD)-equipped angiography machines are increasingly used for neuro-angiographic imaging. During intracranial stent-assisted coil embolization procedures, it is very important to clearly and quickly visualize stent shape after deployment in the vessel. It is necessary to quickly visualize stents by cone-beam computed tomography (CBCT). The aim of this study was to compare CBCTs at 10 and 20 s, and to confirm that this method is useful for neuro-endovascular treatment procedures.

Materials and methods: We treated 30 patients with wide-necked intracranial aneurysms with a flexible, self-expanding neurovascular stent and subsequent aneurysm embolization with platinum micro-coils. We performed the CBCT after stent deployment. We compared the 10 s and 20 s CBCTs, using the full width one-half maximum (FWHM) visualization.

Results: Accurate stent placement with subsequent coil occlusion of the aneurysms was feasible in all patients. Stent struts were clearly visualized on both 10 s and 20 s CBCTs. Importantly, 10 s CBCT can reduce the radiation dose by about 42%, compared with 20 s CBCT. Performing 10 s CBCT with a 14% dilution of the contrast medium may significantly improve image acquisition during stent-assisted coil embolization.

Conclusions: Reduced-dose, 10 s CBCT can visualize stents in clinical cases, while significantly reducing radiation exposure.

Keywords: Aneurysm; brain; coil embolization; cone-beam computed tomography; embolization; flat panel detector; radiation dose; radiation exposure; stent.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Cerebral Angiography
  • Cone-Beam Computed Tomography / methods*
  • Contrast Media
  • Embolization, Therapeutic / instrumentation
  • Embolization, Therapeutic / methods*
  • Female
  • Humans
  • Intracranial Aneurysm / diagnostic imaging*
  • Intracranial Aneurysm / therapy*
  • Iopamidol
  • Male
  • Middle Aged
  • Radiation Dosage
  • Radiation Protection
  • Radiographic Image Interpretation, Computer-Assisted
  • Radiography, Interventional / methods*
  • Stents*
  • Treatment Outcome

Substances

  • Contrast Media
  • Iopamidol