Severe bilateral cerebellar edema from ingestion of ketamine: case report

J Neurosurg Pediatr. 2017 Oct;20(4):393-396. doi: 10.3171/2017.5.PEDS16695. Epub 2017 Aug 15.

Abstract

The use of ketamine as a drug of abuse has increased and so too has the risk of accidental overdose. Here, the authors report the case of a 10-month-old infant who inadvertently ingested ketamine. The child demonstrated severe cerebellar swelling that required emergency surgical intervention. The authors describe the clinical course of this child and present the radiographic characteristics of the brain. The imaging characteristics were not consistent with purely anoxic injury, thus suggesting a specific effect of this drug. To the authors' knowledge, similar imaging characteristics in this context have not been described.

Keywords: EVD = external ventricular drain; PEG = percutaneous endoscopic gastrostomy; cerebellar; edema; ketamine; pediatric neurosurgery.

Publication types

  • Case Reports

MeSH terms

  • Analgesics / adverse effects*
  • Brain Edema / chemically induced*
  • Brain Edema / diagnostic imaging
  • Brain Edema / pathology*
  • Cerebellum / diagnostic imaging
  • Cerebellum / pathology*
  • Female
  • Humans
  • Infant
  • Ketamine / adverse effects*
  • Magnetic Resonance Imaging

Substances

  • Analgesics
  • Ketamine