Abstract
Extracranial metastasis is an unusual complication of most types of primary intracranial tumor. Approximately one-third of reported cases of primary intracranial choriocarcinoma have been associated with pulmonary tumor metastasis. The prognosis of such patients has been uniformly fatal. This report describes a probable long-term survivor of primary intracranial choriocarcinoma wit pulmonary metastasis. The patient had a complete response to combination chemotherapy with cisplatin, etoposide, and bleomycin and is surviving free of disease >3 years from diagnosis.
MeSH terms
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Antibiotics, Antineoplastic / administration & dosage
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Antineoplastic Agents / administration & dosage
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Antineoplastic Agents, Phytogenic / administration & dosage
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Antineoplastic Combined Chemotherapy Protocols / therapeutic use
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Bleomycin / administration & dosage
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Brain Neoplasms / pathology*
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Brain Neoplasms / surgery
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Child
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Choriocarcinoma / pathology*
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Choriocarcinoma / secondary*
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Choriocarcinoma / surgery
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Cisplatin / administration & dosage
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Etoposide / administration & dosage
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Follow-Up Studies
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Humans
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Lung Neoplasms / pathology
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Lung Neoplasms / secondary*
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Male
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Prognosis
Substances
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Antibiotics, Antineoplastic
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Antineoplastic Agents
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Antineoplastic Agents, Phytogenic
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Bleomycin
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Etoposide
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Cisplatin