Technical considerations on intra-arterial papaverine hydrochloride for cerebral vasospasm

Neuroradiology. 1997 Feb;39(2):90-8. doi: 10.1007/s002340050373.

Abstract

Intra-arterial infusion of papaverine hydrochloride for subarachnoid hemorrhage-induced cerebral vasospasm has become an adjunctive endovascular therapy along with cerebral angioplasty. Our knowledge concerning the mechanism of action, method of administration and potential side effects of this therapeutic alternative are reviewed.

Publication types

  • Review

MeSH terms

  • Angioplasty, Balloon
  • Cerebral Angiography / drug effects
  • Combined Modality Therapy
  • Humans
  • Injections, Intra-Arterial
  • Ischemic Attack, Transient / diagnostic imaging
  • Ischemic Attack, Transient / drug therapy*
  • Papaverine / administration & dosage*
  • Papaverine / adverse effects
  • Subarachnoid Hemorrhage / diagnostic imaging
  • Subarachnoid Hemorrhage / drug therapy*
  • Treatment Outcome
  • Vasodilator Agents / administration & dosage*
  • Vasodilator Agents / adverse effects

Substances

  • Vasodilator Agents
  • Papaverine