Abstract
Intra-arterial infusion of papaverine hydrochloride for subarachnoid hemorrhage-induced cerebral vasospasm has become an adjunctive endovascular therapy along with cerebral angioplasty. Our knowledge concerning the mechanism of action, method of administration and potential side effects of this therapeutic alternative are reviewed.
MeSH terms
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Angioplasty, Balloon
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Cerebral Angiography / drug effects
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Combined Modality Therapy
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Humans
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Injections, Intra-Arterial
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Ischemic Attack, Transient / diagnostic imaging
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Ischemic Attack, Transient / drug therapy*
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Papaverine / administration & dosage*
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Papaverine / adverse effects
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Subarachnoid Hemorrhage / diagnostic imaging
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Subarachnoid Hemorrhage / drug therapy*
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Treatment Outcome
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Vasodilator Agents / administration & dosage*
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Vasodilator Agents / adverse effects
Substances
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Vasodilator Agents
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Papaverine