Effect of Time Elapsed since Gadolinium Administration on Atherosclerotic Plaque Enhancement in Clinical Vessel Wall MR Imaging Studies

AJNR Am J Neuroradiol. 2019 Oct;40(10):1709-1711. doi: 10.3174/ajnr.A6191. Epub 2019 Sep 12.

Abstract

Vessel wall MR imaging is a useful tool for the evaluation of intracranial atherosclerotic disease. Enhancement can be particularly instructive. This study investigated the impact of the duration between contrast administration and image acquisition. The cohort with the longest duration had the greatest increase in signal intensity change. When using vessel wall MR imaging to assess intracranial atherosclerotic disease, protocols should be designed to maximize the duration between contrast administration and image acquisition to best demonstrate enhancement.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Contrast Media
  • Female
  • Gadolinium
  • Humans
  • Image Interpretation, Computer-Assisted / methods*
  • Intracranial Arteriosclerosis / diagnostic imaging*
  • Magnetic Resonance Angiography / methods*
  • Male
  • Plaque, Atherosclerotic / diagnostic imaging*
  • Retrospective Studies
  • Time Factors

Substances

  • Contrast Media
  • Gadolinium