Revenge of the phages: defeating bacterial defences
JE Samson, AH Magadán, M Sabri… - Nature Reviews …, 2013 - nature.com
Bacteria and their viral predators (bacteriophages) are locked in a constant battle. In order
to proliferate in phage-rich environments, bacteria have an impressive arsenal of defence …
to proliferate in phage-rich environments, bacteria have an impressive arsenal of defence …
The CRISPR/Cas bacterial immune system cleaves bacteriophage and plasmid DNA
Bacteria and Archaea have developed several defence strategies against foreign nucleic
acids such as viral genomes and plasmids. Among them, clustered regularly interspaced short …
acids such as viral genomes and plasmids. Among them, clustered regularly interspaced short …
[HTML][HTML] Cleavage of Phage DNA by the Streptococcus thermophilus CRISPR3-Cas System
AH Magadán, MÈ Dupuis, M Villion, S Moineau - PloS one, 2012 - journals.plos.org
Streptococcus thermophilus, similar to other Bacteria and Archaea, has developed defense
mechanisms to protect cells against invasion by foreign nucleic acids, such as virus …
mechanisms to protect cells against invasion by foreign nucleic acids, such as virus …
CRISPR-Cas and restriction–modification systems are compatible and increase phage resistance
MÈ Dupuis, M Villion, AH Magadán… - Nature communications, 2013 - nature.com
Bacteria have developed a set of barriers to protect themselves against invaders such as
phage and plasmid nucleic acids. Different prokaryotic defence systems exist and at least two …
phage and plasmid nucleic acids. Different prokaryotic defence systems exist and at least two …
Multiplex PCR for the detection and identification of dairy bacteriophages in milk
…, AG Binetti, MC Martín, M Fernández, AH Magadan… - Food …, 2007 - Elsevier
Bacteriophage infections of starter lactic acid bacteria are a serious risk in the dairy industry.
Phage infection can lead to slow lactic acid production or even the total failure of …
Phage infection can lead to slow lactic acid production or even the total failure of …
[HTML][HTML] Phage-host interactions in Streptococcus thermophilus: Genome analysis of phages isolated in Uruguay and ectopic spacer acquisition in CRISPR array
R Achigar, AH Magadán, DM Tremblay… - Scientific reports, 2017 - nature.com
Three cos-type virulent Streptococcus thermophilus phages were isolated from failed
mozzarella production in Uruguay. Genome analyses showed that these phages are similar to …
mozzarella production in Uruguay. Genome analyses showed that these phages are similar to …
Combined approach to lysis utilizing eptifibatide and recombinant tissue plasminogen activator in acute ischemic stroke–enhanced regimen stroke trial
…, J Lynch, J Merino, R Menon, J Freeman, A Magadan… - Stroke, 2013 - Am Heart Assoc
Background and Purpose— In a previous study, 0.3 and 0.45 mg/kg of intravenous recombinant
tissue plasminogen activator (rt-PA) were safe when combined with eptifibatide 75 mcg/…
tissue plasminogen activator (rt-PA) were safe when combined with eptifibatide 75 mcg/…
The CRISPR‐Cas immune system and genetic transfers: Reaching an equilibrium
JE Samson, AH Magadan… - Plasmids: Biology and …, 2015 - Wiley Online Library
In 1987 Ishino et al. (1) sequenced the Escherichia coli alkaline phosphatase isozyme conversion
gene (iap). Downstream of iap, they observed an array of short repeats (29 nucleotides…
gene (iap). Downstream of iap, they observed an array of short repeats (29 nucleotides…
Stroke mismatch volume with the use of ABC/2 is equivalent to planimetric stroke mismatch volume
…, JK Lynch, AW Hsia, A Magadán… - American Journal …, 2013 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: In the clinical setting, there is a need to perform mismatch
measurements quickly and easily on the MR imaging scanner to determine the specific …
measurements quickly and easily on the MR imaging scanner to determine the specific …
Negative diffusion-weighted imaging after intravenous tissue-type plasminogen activator is rare and unlikely to indicate averted infarction
Background and Purpose— Some patients treated with intravenous (IV) tissue-type plasminogen
activator (tPA) have negative diffusion-weighted imaging (DWI) on follow-up imaging. …
activator (tPA) have negative diffusion-weighted imaging (DWI) on follow-up imaging. …
