The 2010 McDonald criteria for the diagnosis of multiple sclerosis are widely used in research
and clinical practice. Scientific advances in the past 7 years suggest that they might no …

Neuromyelitis optica (NMO) is an inflammatory CNS syndrome distinct from multiple
sclerosis (MS) that is associated with serum aquaporin-4 immunoglobulin G antibodies (AQP4-IgG). …

The 2015 Magnetic Resonance Imaging in Multiple Sclerosis and 2016 Consortium of Multiple
Sclerosis Centres guidelines on the use of MRI in diagnosis and monitoring of multiple …

Background An evolving understanding of the immunopathogenesis of multiple sclerosis
suggests that depleting B cells could be useful for treatment. We studied ocrelizumab, a …

Background B cells influence the pathogenesis of multiple sclerosis. Ocrelizumab is a humanized
monoclonal antibody that selectively depletes CD20+ B cells. Methods In two identical …

Myelin-oligodendrocyte glycoprotein antibody-associated disease (MOGAD) is a recently
identified autoimmune disorder that presents in both adults and children as CNS demyelination…

Since its initial reports in the 19th century, neuromyelitis optica (NMO) had been thought to
involve only the optic nerves and spinal cord. However, the discovery of highly specific anti–…

Various magnetic resonance (MR) techniques are used to study the pathological evolution
of demyelinating diseases, such as multiple sclerosis (MS). However, few studies have …

We propose a novel segmentation approach based on deep 3D convolutional encoder
networks with shortcut connections and apply it to the segmentation of multiple sclerosis (MS) …

MRI has improved the diagnostic work-up of multiple sclerosis, but inappropriate image
interpretation and application of MRI diagnostic criteria contribute to misdiagnosis. Some …