Takeoff and landing are critical phases in a flight. To better understand the functional
importance of the kinematic adjustments birds use to execute these flight modes, we studied the …

BACKGROUND AND PURPOSE: Sonography, CT, and MR imaging are commonly used to
screen for neonatal intracranial ischemia and hemorrhage, yet few studies have attempted to …

We tested the applicability and signal quality of a 16 channel dry electroencephalography (EEG)
system in a laboratory environment and in a car under controlled, realistic conditions. …

Src homology 2 (SH2) domains play a central role in signal transduction. Although many
SH2 domains have been validated as drug targets, their structural similarity makes …

The transcription factor STAT5b is a target for tumour therapy. We recently reported catechol
bisphosphate and derivatives such as Stafib-1 as the first selective inhibitors of the STAT5b …

Ascending or descending locomotion involves a change in potential energy(PE) and a
corresponding change in power requirement. We sought to test whether the mechanical power …

Polo-like kinase (PLK1) has been identified as a potential target for cancer treatment. Although
a number of small molecules have been investigated as PLK1 inhibitors, many of which …

Polo‐like kinase 1 (Plk1), a key player in mitosis, is overexpressed in a wide range of tumor
types and has been validated as a target for tumor therapy. In addition to its N‐terminal …

The signal transducer and activation of transcription (STAT) proteins are a family of Src
homology 2 (SH2) domain-containing transcription factors. The family member STAT4 is a …

Inhibition of protein-protein interactions by small molecules offers tremendous opportunities
for basic research and drug development. One of the fundamental challenges of this …