Importance Although use of oral anticoagulants (OACs) is increasing, there is a substantial
lack of data on how to treat OAC-associated intracerebral hemorrhage (ICH). Objective To …

There has been a consistent gap in understanding how TNF-α neutralization affects the
disease state of arthritis patients so rapidly, considering that joint inflammation in rheumatoid …

The sellar and parasellar region is an anatomically complex area where a number of
neoplastic, infectious, inflammatory, developmental and vascular pathologies can occur. …

Background and Purpose— There is only limited knowledge on the time course of
perihemorrhagic edema (PHE) after intracerebral hemorrhage (ICH). We aimed to investigate the …

Neurodegeneration and brain edema are hallmarks of human malignant brain tumors. Here
we show that genetic or pharmacological inhibition of the glutamate transporter xCT (X c − …

✓ Acute ischemia in the complete territory of the carotid artery may lead to massive cerebral
edema with raised intracranial pressure and progression to coma and death due to uncal, …

Background and Purpose. To study whether computed tomography (CT) can measure the
water content of early ischemic edema. Methods. The authors obtained cranial CT in 5 groups …

Haemodynamic factors, in particular wall shear stresses (WSSs) may have significant impact
on growth and rupture of cerebral aneurysms. Without a means to measure WSS reliably in …

BACKGROUND AND PURPOSE: Currently available stents for intracranial use usually are
balloon-expandable coronary stents that carry the risk of damaging a dysplastic segment of …

BACKGROUND AND PURPOSE: Aneurysmal rupture during endovascular treatment is one
of the most feared complications of endovascular aneurysm therapy. The purpose of this …